Granulomatous response to invasive pulmonary aspergillosis in an immunotherapy-naive host, a maladaptive response?
نویسندگان
چکیده
منابع مشابه
Host biomarkers of invasive pulmonary aspergillosis to monitor therapeutic response.
Invasive pulmonary aspergillosis (IPA) is a life-threatening disease of immunocompromised patients that requires aggressive therapy. Detection of the disease and monitoring of the therapeutic response during IPA are complex, and current molecular diagnostics are not suitably robust. Here, we explored proteomic profiles of bronchoalveolar lavage fluid (BALF) specimens from a persistently neutrop...
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SUMMARY Aspergillosis is an infectious disease caused by genus aspergillos species. Aspergilli are ab undant in the environment, they Jive in soil as saprophyte deriving nutrient, from dead plants and animal matters. The genus aspergillos in characterized by the formation of distinctive conidiophores giving rise to conidias which can spread by air and are able to reside on the body surface spe...
متن کاملHost Biomarkers of Invasive Pulmonary Aspergillosis to Monitor Therapeutic 1 Response 2 3 4
19 Invasive pulmonary aspergillosis (IPA) is a life threatening disease of 20 immunocompromised patients that requires aggressive therapy. Detection and monitoring 21 therapeutic response during IPA is complex and current molecular diagnostics are not 22 suitably robust. Here, we explored proteomic profiles of bronchoalveolar lavage fluid 23 (BALF) specimens from a persistently neutropenic rabb...
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TO THE EDITOR—In a recent article published in Clinical Infectious Diseases, Nouér and colleagues recommend that the Aspergillus galactomannan index (GMI)–based response criteria be used as a primary endpoint in clinical trials of invasive aspergillosis (IA) rather than the European Organisation for Research and Treatment of Cancer/Mycoses Study Group (EORTC/MSG) outcome definitions [1] based o...
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A 54 year-old male patient was admitted to our clinic with dyspnea, dry cough and fever. Chest X-ray revealed pneumonic infiltration with air bronchograms involving all zones of right hemithorax. We observed radiological and clinical progress despite ceftriaxone, clarithromicin and bronchodilator for chronic obstructive pulmonary disease. The gram staining of bronchoalveolar lavage showed funga...
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ژورنال
عنوان ژورنال: Respiratory Medicine Case Reports
سال: 2018
ISSN: 2213-0071
DOI: 10.1016/j.rmcr.2018.05.017